Effects of escins Ia, Ib, IIa, and IIb from horse chestnut, the seeds of Aesculus hippocastanum L., on acute inflammation in animals
H Matsuda, Y Li, T Murakami, K NINOMIYA… - Biological and …, 1997 - jstage.jst.go.jp
MATERIALS AND METHODS Animals Male Wistar rats and male ddY mice were purchased
from Kiwa Laboratory Animal Co., Ltd. The animals were maintained in a 12h light—dark
cycle at a constant temperature of23 $2 “C and were fed a standard laboratory chow (MF,
Oriental Yeast Co., Ltd). They were fasted for 15 '18h prior to experiments, but were supplied
with water ad libitam. Test samples were suspended in 2% acacia solution and were given
orally at 10 ml/kg in each experiment. The experiments were performed in conscious …
from Kiwa Laboratory Animal Co., Ltd. The animals were maintained in a 12h light—dark
cycle at a constant temperature of23 $2 “C and were fed a standard laboratory chow (MF,
Oriental Yeast Co., Ltd). They were fasted for 15 '18h prior to experiments, but were supplied
with water ad libitam. Test samples were suspended in 2% acacia solution and were given
orally at 10 ml/kg in each experiment. The experiments were performed in conscious …
Antiinflammatory effects of escins Ia, Ib, IIa, and IIb from horse chestnut, the seeds of Aesculus hippocastanum L.
H Matsuda, Y Li, T Murakami, K Ninomiya… - Bioorganic & Medicinal …, 1997 - Elsevier
We have investigated the effects of escins Ia, Ib, IIa, and IIb isolated from horse chestnut, the
seeds of Aesculus hippocastanum L. and desacylescins I and II obtained by alkaline
hydrolysis of escins on acute inflammation in experimental animal models, and some
structure-requirements of escins for the activity was obtained.
seeds of Aesculus hippocastanum L. and desacylescins I and II obtained by alkaline
hydrolysis of escins on acute inflammation in experimental animal models, and some
structure-requirements of escins for the activity was obtained.
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